NME1

Across TCGA patient cohorts, NME1 mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible NME1-associated genes across cancer lineages are RN7SL429P, MIR6796, and LINC01609. Each is linked with NME1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NME1-to-partner and partner-to-NME1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL429P grouped by NME1-low versus NME1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME1→partner) and Y-score (partner→NME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL429P →	+0.103	+4.923	<.001	.002	3	2
LIHC	MIR6796 →	+0.570	+5.268	<.001	.006	3	1
SKCM	LINC01609 →	+0.183	+5.867	<.001	.003	3	1
SKCM	ABCB10P3 →	+0.031	+5.436	<.001	.005	3	1
LIHC	RBMY1F →	+0.145	+6.149	<.001	.002	3	1
LIHC	OR6S1 →	+0.044	+5.033	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

RN7SL429P by NME1 expression — UCEC

Explore this box plot interactively →