NMBR-AS1

Across TCGA pan-cancer cohorts, NMBR-AS1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated NMBR-AS1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher NMBR-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NMBR-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

STAD, THCA, and READ are the cancer types where NMBR-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	II,III,IV	0.337	0.552	.009	63	view →
THCA	DFS	Tertile	III,IV	0.679	0.939	<.001	57	view →
READ	DFS	Tertile	All	0.234	0.703	.004	54	view →
LUSC	OS	Tertile	III,IV	0.315	0.689	.002	54	view →
ESCA	DFS	Tertile	II,III,IV	0.270	0.534	.026	36	view →
HNSC	OS	Tertile	All	0.217	0.616	<.001	27	view →
BRCA	DFS	Tertile	IV	0.645	0.229	.036	12	view →
KIRC	DFS	Tertile	III,IV	0.624	0.761	.044	12	view →
SKCM	DFS	Tertile	III,IV	0.015	0.648	<.001	9	view →
KIRP	OS	Tertile	All	0.856	0.954	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

NMBR-AS1–STAD (DFS)

Open the STAD breakdown →