Across TCGA patient cohorts, NMB protein abundance is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NMB-associated genes across cancer lineages are GGTLC2, CABP7, and COTL1. Each is linked with NMB in more than 1 cancer types. Because this analysis shows association rather than direction, both NMB-to-partner and partner-to-NMB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMB→partner) and Y-score (partner→NMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GGTLC2 →	-0.122	-0.747	.001	.004	3	1
GBM	CABP7 →	-1.594	-0.922	<.001	.005	3	1
GBM	COTL1 →	-0.673	-0.854	<.001	.002	3	1
GBM	EHD4 →	-0.541	-0.781	.004	.005	3	1
GBM	IL27RA →	-0.505	-0.628	.005	.003	3	1
GBM	LIMK1 →	-0.496	-0.706	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

Exploration

NMB survival (RNA) · tumor vs normal (RNA) · all NMB data types