NMB

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NMB mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMB-associated genes across cancer lineages are LINC02336, LINC02348, and LINC02371. Each is linked with NMB in more than 1 cancer types. Because this analysis shows association rather than direction, both NMB-to-partner and partner-to-NMB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMB→partner) and Y-score (partner→NMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC02336 →+0.297+4.226<.001.00831
UCECLINC02348 →+0.602+3.778<.001.00631
UCECLINC02371 →+0.311+3.812<.001.00531
UCECRNA5SP411 →+1.649+3.393<.001.00731
HNSCPIGQP1 →+0.089+5.912.002.00231
HNSCOFD1P6Y →+0.008+5.241.009.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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