NLRX1

Across TCGA cell cohorts, NLRX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,329 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NLRX1-associated GO terms across cancer lineages are Regulation of early endosome to late endosome transport, Regulation of protein localization to endoplasmic reticulum, and Negative regulation of calcium ion export across plasma membrane. Each is linked with NLRX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both NLRX1-to-partner and partner-to-NLRX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of early endosome to late endosome transport grouped by NLRX1-low versus NLRX1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRX1→partner) and Y-score (partner→NLRX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of early endosome to late endosome transport →	+0.133	+1.207	<.001	<.001	3	12
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.130	+0.884	.001	.001	3	11
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.082	+1.621	<.001	.001	3	11
LARGE_INTESTINE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.175	+1.197	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.057	+0.989	<.001	<.001	3	11
BONE	Regulation of Golgi inheritance →	+0.156	+2.118	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,329 associations by consensus.

Regulation of early endosome to late endosome transport by NLRX1 expression — KIDNEY

Explore this box plot interactively →