NLRP7

Across TCGA cell cohorts, NLRP7 RNA expression is significantly associated with the RNA expression of many other genes, with 2,335 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NLRP7-associated genes across cancer lineages are NLRP2, NCR1, and ANKRD35. Each is linked with NLRP7 in more than 4 cancer types. Because this analysis shows association rather than direction, both NLRP7-to-partner and partner-to-NLRP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRP7 versus NLRP2 in LUNG_NSCLC_LUAD, with a Pearson correlation of 0.23.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP7→partner) and Y-score (partner→NLRP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	NLRP2 →	+3.188	+0.134	<.001	<.001	3	5
BLOOD_Myeloma	NCR1 →	+0.102	+3.275	.001	<.001	3	4
URINARY_TRACT	ANKRD35 →	+0.632	+1.103	<.001	<.001	2	4
OVARY	EPS8L1 →	+3.817	+0.861	<.001	<.001	3	3
URINARY_TRACT	RAB25 →	+5.418	+0.837	<.001	.004	2	4
URINARY_TRACT	ST14 →	+3.617	+0.976	<.001	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,335 associations by consensus.

NLRP7 vs NLRP2 — LUNG_NSCLC_LUAD

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