NLRP7

Across TCGA cell cohorts, NLRP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 878 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NLRP7-associated GO terms across cancer lineages are Cellular response to folic acid, 3'-UTR-mediated mRNA stabilization, and Cellular response to prostaglandin E stimulus. Each is linked with NLRP7 in more than 4 cancer types. Because this analysis shows association rather than direction, both NLRP7-to-partner and partner-to-NLRP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to folic acid grouped by NLRP7-low versus NLRP7-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP7→partner) and Y-score (partner→NLRP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Cellular response to folic acid →	+0.895	+1.426	<.001	.007	3	4
LUNG_NSCLC_LUAD	3'-UTR-mediated mRNA stabilization →	+0.073	+0.096	<.001	.001	3	4
LUNG_NSCLC_LUAD	Cellular response to prostaglandin E stimulus →	+0.074	+0.094	.004	.006	3	4
URINARY_TRACT	Glycerolipid biosynthetic process →	+0.048	+1.165	<.001	.007	3	4
KIDNEY	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.070	+0.027	.002	.007	3	4
LUNG_NSCLC_LUAD	Endothelial cell proliferation →	-0.075	-0.087	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 878 associations by consensus.

Cellular response to folic acid by NLRP7 expression — BLOOD_Lymphoma

Explore this box plot interactively →