Q-omics provides the consensus-scored NLRP3P1 profile across patient tissues and cancer cell-line models. NLRP3P1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, NLRP3P1 is differentially expressed in 15, with the highest sampling consensus in HNSC. Additionally, NLRP3P1 RNA expression shows 15,010 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCEC, HNSC, and TGCT as cancer lineages where NLRP3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NLRP3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NLRP3P1 survival associations across molecular data types. NLRP3P1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NLRP3P1 RNA expression–survival associations across cancer types. High NLRP3P1 expression shows unfavorable associations in UCEC, HNSC, STAD, LIHC, KICH and ACC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for NLRP3P1 RNA expression.
This table summarizes NLRP3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NLRP3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NLRP3P1 shows higher tumor expression in HNSC, KIRC, THCA, LUAD, LUSC and KIRP. The HNSC box plot shows higher NLRP3P1 RNA expression in tumor versus normal tissue (log2 FC = +1.262, t-test p < 0.001).
This table shows molecular features associated with NLRP3P1 in patient tissues and cancer cell lines. In patient samples, NLRP3P1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
