NLRP12

Across TCGA patient cohorts, NLRP12 protein abundance is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NLRP12-associated genes across cancer lineages are RPL22L1, GPR101, and OR4K11P. Each is linked with NLRP12 in more than 1 cancer types. Because this analysis shows association rather than direction, both NLRP12-to-partner and partner-to-NLRP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRP12 versus RPL22L1 in BRCA, with a Pearson correlation of 0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP12→partner) and Y-score (partner→NLRP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPL22L1 →	+1.274	+2.435	.004	.003	3	1
BRCA	GPR101 →	-0.046	-1.690	<.001	.008	3	1
BRCA	OR4K11P →	-0.176	-1.575	<.001	.006	3	1
BRCA	FER1L6-AS1 →	-0.076	-1.575	<.001	.006	3	1
BRCA	KRTAP21-1 →	-0.386	-1.575	<.001	.006	3	1
BRCA	RNU4-4P →	-0.986	-1.575	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

NLRP12 vs RPL22L1 — BRCA

Explore this scatter interactively →