NLRP12

Across TCGA cell cohorts, NLRP12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,271 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NLRP12-associated GO terms across cancer lineages are Negative regulation of epithelial cell apoptotic process, Sulfur amino acid catabolic process, and Regulation of TOR signaling. Each is linked with NLRP12 in more than 3 cancer types. Because this analysis shows association rather than direction, both NLRP12-to-partner and partner-to-NLRP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of epithelial cell apoptotic process grouped by NLRP12-low versus NLRP12-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP12→partner) and Y-score (partner→NLRP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of epithelial cell apoptotic process →	+0.086	+0.544	.003	.009	3	4
BLOOD_Leukemia	Sulfur amino acid catabolic process →	+0.078	+0.815	.001	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of TOR signaling →	+0.018	+0.426	.005	.002	3	3
LUNG_NSCLC_LUAD	Maintenance of blood-brain barrier →	+0.130	+0.491	.002	.007	3	3
UPPER_AERODIGESTIVE_TRACT	Protein K11-linked ubiquitination →	+0.049	+0.049	.008	.009	3	3
STOMACH	Response to starvation →	+0.062	+0.063	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,271 associations by consensus.

Negative regulation of epithelial cell apoptotic process by NLRP12 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →