NLRP11

Across TCGA cell cohorts, NLRP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,998 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NLRP11-associated GO terms across cancer lineages are Positive regulation of axon guidance, Locomotory exploration behavior, and Response to mitochondrial depolarisation. Each is linked with NLRP11 in more than 7 cancer types. Because this analysis shows association rather than direction, both NLRP11-to-partner and partner-to-NLRP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of axon guidance grouped by NLRP11-low versus NLRP11-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP11→partner) and Y-score (partner→NLRP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of axon guidance →	+0.847	+0.137	.002	.002	2	8
OVARY	Locomotory exploration behavior →	+0.185	+0.254	<.001	.006	3	6
BLOOD_Myeloma	Response to mitochondrial depolarisation →	+0.106	+2.637	.004	.005	3	6
OESOPHAGUS	Mitochondrial tRNA pseudouridine synthesis →	+0.104	+0.113	<.001	.008	2	6
OVARY	Regulation of telomere maintenance →	+0.050	+0.225	.001	.006	3	5
PANCREAS	Negative regulation of insulin secretion →	-0.142	-0.157	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,998 associations by consensus.

Positive regulation of axon guidance by NLRP11 expression — PANCREAS

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