NLRP10

Across TCGA patient cohorts, NLRP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,078 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NLRP10-associated GO terms across cancer lineages are Keratinocyte proliferation, Regulation of wound healing, and Skin epidermis development. Each is linked with NLRP10 in more than 16 cancer types. Because this analysis shows association rather than direction, both NLRP10-to-partner and partner-to-NLRP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocyte proliferation grouped by NLRP10-low versus NLRP10-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP10→partner) and Y-score (partner→NLRP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Keratinocyte proliferation →	+0.078	+0.559	<.001	<.001	3	17
STAD	Regulation of wound healing →	+0.041	+0.080	<.001	<.001	3	17
ESCA	Skin epidermis development →	+0.058	+0.343	<.001	<.001	3	16
STAD	Negative regulation of response to wounding →	+0.030	+0.073	<.001	<.001	3	15
ESCA	Regulation of epidermis development →	+0.061	+0.457	<.001	<.001	3	15
STAD	Cellular response to interleukin-1 →	+0.045	+0.098	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,078 associations by consensus.

Keratinocyte proliferation by NLRP10 expression — ESCA

Explore this box plot interactively →