NLRP10

Across TCGA patient cohorts, NLRP10 protein abundance is significantly associated with the RNA expression of many other genes, with 357 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NLRP10-associated genes across cancer lineages are SLC5A1, TPTEP1, and CYP2D6. Each is linked with NLRP10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NLRP10-to-partner and partner-to-NLRP10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRP10 versus SLC5A1 in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP10→partner) and Y-score (partner→NLRP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC5A1 →	+2.013	+1.454	<.001	.001	3	1
HNSC	TPTEP1 →	-0.669	-0.860	.001	.002	3	1
HNSC	CYP2D6 →	-0.685	-1.301	.001	.002	3	1
HNSC	COCH →	-0.827	-0.811	<.001	.004	3	1
HNSC	CHRDL1 →	-2.320	-1.243	<.001	<.001	3	1
HNSC	PORCN →	+0.837	+1.211	.009	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 357 associations by consensus.

NLRP10 vs SLC5A1 — HNSC

Explore this scatter interactively →