NLRP10

Across TCGA cell cohorts, NLRP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,020 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NLRP10-associated GO terms across cancer lineages are Dentinogenesis, Protein activation cascade, and Blood coagulation, fibrin clot formation. Each is linked with NLRP10 in more than 12 cancer types. Because this analysis shows association rather than direction, both NLRP10-to-partner and partner-to-NLRP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dentinogenesis grouped by NLRP10-low versus NLRP10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP10→partner) and Y-score (partner→NLRP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dentinogenesis →	+2.513	+1.008	<.001	.008	3	13
SOFT_TISSUE	Protein activation cascade →	+0.328	+0.486	<.001	.001	3	12
SOFT_TISSUE	Blood coagulation, fibrin clot formation →	+0.342	+0.656	<.001	.009	3	12
BONE	Negative regulation of dendritic cell apoptotic process →	+1.963	+1.283	<.001	.007	3	11
OVARY	Blood coagulation, intrinsic pathway →	+0.190	+0.506	<.001	.002	3	11
BONE	Regulation of plasma membrane repair →	+0.429	+1.260	<.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,020 associations by consensus.

Dentinogenesis by NLRP10 expression — BONE

Explore this box plot interactively →