NLRC5

Across TCGA patient cohorts, NLRC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,732 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NLRC5-associated proteins across cancer lineages are PSMB10, PSMB6, and PSMB9. Each is linked with NLRC5 in more than 9 cancer types. Because this analysis shows association rather than direction, both NLRC5-to-partner and partner-to-NLRC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRC5 versus PSMB10 in GBM, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRC5→partner) and Y-score (partner→NLRC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSMB10 →	+0.677	+1.203	<.001	<.001	3	10
CCRCC	PSMB6 →	-0.508	-0.755	<.001	<.001	3	10
BRCA	PSMB9 →	+0.535	+1.081	<.001	<.001	3	10
HNSC	APOL3 →	+0.813	+0.819	<.001	<.001	3	10
HNSC	OAS2 →	+0.814	+0.829	<.001	<.001	3	10
OV	PARP14 →	+0.500	+0.986	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,732 associations by consensus.

NLRC5 vs PSMB10 — GBM

Explore this scatter interactively →