NLRC3

Across TCGA pan-cancer cohorts, NLRC3 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NLRC3 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NLRC3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NLRC3 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD and HNSC are the cancer types where NLRC3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	1.000	0.325	.011	12	view →
HNSC	DFS	Median	IV	0.621	0.891	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NLRC3–LUAD (DFS)

Open the LUAD breakdown →