NLRC3

Across TCGA patient cohorts, NLRC3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,267 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NLRC3-associated genes across cancer lineages are MEFV, TMEM176B, and ADGRG3. Each is linked with NLRC3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NLRC3-to-partner and partner-to-NLRC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRC3 versus MEFV in HNSC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRC3→partner) and Y-score (partner→NLRC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEFV →	+1.010	+1.938	.005	.005	3	3
HNSC	TMEM176B →	+1.764	+2.355	.002	<.001	3	3
HNSC	ADGRG3 →	+1.510	+1.582	.002	.009	3	3
HNSC	SLC17A9 →	+1.233	+2.281	.006	.002	2	3
LUAD	PPP1R16B →	+0.831	+0.497	.001	.004	3	2
LSCC	TNFSF13B →	+0.941	+0.596	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,267 associations by consensus.

NLRC3 vs MEFV — HNSC

Explore this scatter interactively →