NLK

Across TCGA patient cohorts, NLK protein abundance is significantly associated with the RNA expression of many other genes, with 1,442 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NLK-associated genes across cancer lineages are CST4, FA2H, and ACVR1B. Each is linked with NLK in more than 1 cancer types. Because this analysis shows association rather than direction, both NLK-to-partner and partner-to-NLK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLK versus CST4 in LUAD, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLK→partner) and Y-score (partner→NLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CST4 →	+2.683	+0.763	.003	.005	3	1
LUAD	FA2H →	+2.273	+0.753	.003	.006	3	1
LUAD	ACVR1B →	-1.350	-0.763	.003	.005	3	1
LUAD	TLN1 →	-0.201	-0.606	.005	.002	3	1
LUAD	TPMT →	-0.541	-0.606	<.001	.002	3	1
LUAD	SIGMAR1 →	-0.649	-0.606	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,442 associations by consensus.

NLK vs CST4 — LUAD

Explore this scatter interactively →