NLK

Across TCGA cell cohorts, NLK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,385 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NLK-associated GO terms across cancer lineages are Stress granule assembly, Heterochromatin formation, and Epigenetic regulation of gene expression. Each is linked with NLK in more than 12 cancer types. Because this analysis shows association rather than direction, both NLK-to-partner and partner-to-NLK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stress granule assembly grouped by NLK-low versus NLK-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLK→partner) and Y-score (partner→NLK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.128	+0.963	<.001	<.001	3	13
STOMACH	Heterochromatin formation →	+0.093	+0.987	<.001	.001	3	13
STOMACH	Epigenetic regulation of gene expression →	+0.068	+0.912	<.001	<.001	3	13
STOMACH	Heterochromatin organization →	+0.073	+0.789	<.001	.001	3	13
STOMACH	Positive regulation of organelle assembly →	+0.076	+1.174	<.001	<.001	3	13
STOMACH	Negative regulation of TOR signaling →	+0.068	+0.799	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,385 associations by consensus.

Stress granule assembly by NLK expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →