NLGN2

Across TCGA patient cohorts, NLGN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,174 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NLGN2-associated proteins across cancer lineages are PCOLCE, P3H3, and TIMP2. Each is linked with NLGN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both NLGN2-to-partner and partner-to-NLGN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLGN2 versus PCOLCE in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NLGN2→partner) and Y-score (partner→NLGN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PCOLCE →	+0.844	+1.520	.002	<.001	3	9
OV	P3H3 →	+0.655	+1.451	.002	<.001	3	8
BRCA	TIMP2 →	+0.693	+0.640	.001	<.001	3	7
BRCA	AEBP1 →	+0.822	+0.855	<.001	<.001	3	7
OV	FN1 →	+1.165	+1.341	.001	.001	3	7
BRCA	RARRES2 →	+0.750	+0.730	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,174 associations by consensus.

NLGN2 vs PCOLCE — OV

Explore this scatter interactively →