NKTR

Across TCGA patient cohorts, NKTR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,778 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NKTR-associated proteins across cancer lineages are QRICH1, LMNB2, and RBSN. Each is linked with NKTR in more than 5 cancer types. Because this analysis shows association rather than direction, both NKTR-to-partner and partner-to-NKTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKTR versus QRICH1 in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKTR→partner) and Y-score (partner→NKTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	QRICH1 →	+0.228	+0.358	<.001	<.001	3	6
CCRCC	LMNB2 →	+0.311	+0.308	<.001	<.001	3	6
GBM	RBSN →	+0.250	+0.383	.001	.001	3	5
LUAD	MRPL47 →	-0.360	-0.253	<.001	<.001	3	5
PDAC	MRPS5 →	-0.350	-0.274	<.001	.002	3	5
GBM	TOP2B →	+0.421	+0.451	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,778 associations by consensus.

NKTR vs QRICH1 — GBM

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