NKTR

Across TCGA patient cohorts, NKTR protein abundance is significantly associated with the RNA expression of many other genes, with 12,313 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NKTR-associated genes across cancer lineages are LILRA1, TARS2, and TAF1A. Each is linked with NKTR in more than 4 cancer types. Because this analysis shows association rather than direction, both NKTR-to-partner and partner-to-NKTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKTR versus LILRA1 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKTR→partner) and Y-score (partner→NKTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LILRA1 →	-0.564	-0.251	.001	<.001	3	5
UCEC	TARS2 →	+0.563	+0.140	<.001	.001	3	5
UCEC	TAF1A →	+0.451	+0.209	.008	<.001	3	5
OV	ANTXR2 →	-0.988	-0.376	<.001	<.001	3	5
GBM	IGFBP7 →	-0.870	-0.208	<.001	.003	3	5
LSCC	GPR89B →	+0.531	+0.205	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,313 associations by consensus.

NKTR vs LILRA1 — GBM

Explore this scatter interactively →