Across TCGA patient cohorts, NKRF RNA expression is significantly associated with the protein abundance of many other proteins, with 17,296 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKRF-associated proteins across cancer lineages are CUL4B, HCFC1, and PHF6. Each is linked with NKRF in more than 7 cancer types. Because this analysis shows association rather than direction, both NKRF-to-partner and partner-to-NKRF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKRF→partner) and Y-score (partner→NKRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CUL4B →	+0.268	+0.550	<.001	<.001	3	7
GBM	HCFC1 →	+0.234	+0.252	.002	.005	2	8
GBM	PHF6 →	+0.437	+0.339	<.001	<.001	3	6
LSCC	THOC2 →	+0.305	+0.575	<.001	<.001	3	6
LSCC	CSE1L →	+0.342	+0.412	<.001	<.001	3	6
LSCC	DDX27 →	+0.444	+0.504	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,296 associations by consensus.

Exploration

NKRF survival (RNA) · tumor vs normal (RNA) · all NKRF data types