Across TCGA patient cohorts, NKRF protein abundance is significantly associated with the RNA expression of many other genes, with 19,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKRF-associated genes across cancer lineages are TIMM8A, DKC1, and SLC25A5. Each is linked with NKRF in more than 9 cancer types. Because this analysis shows association rather than direction, both NKRF-to-partner and partner-to-NKRF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKRF→partner) and Y-score (partner→NKRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TIMM8A →	+0.834	+0.579	<.001	<.001	3	10
UCEC	DKC1 →	+0.946	+0.363	<.001	<.001	2	10
LSCC	SLC25A5 →	+0.826	+0.558	<.001	<.001	3	9
UCEC	TWNK →	+1.118	+0.371	<.001	<.001	3	8
LSCC	RFC5 →	+0.860	+0.514	<.001	<.001	3	8
LSCC	WDR43 →	+0.802	+0.504	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,385 associations by consensus.

Exploration

NKRF survival (RNA) · tumor vs normal (RNA) · all NKRF data types