Across TCGA patient cohorts, NKRF mutation is significantly associated with the RNA expression of many other genes, with 5,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKRF-associated genes across cancer lineages are RNA5SP412, LINC00351, and RNU6-677P. Each is linked with NKRF in more than 1 cancer types. Because this analysis shows association rather than direction, both NKRF-to-partner and partner-to-NKRF results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKRF→partner) and Y-score (partner→NKRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.373	+1.597	<.001	.001	3	2
CESC	LINC00351 →	+0.101	+3.786	<.001	.003	3	2
CESC	RNU6-677P →	+0.456	+3.236	<.001	.005	3	2
CESC	MIR7853 →	+0.210	+4.020	<.001	.009	3	2
CESC	NF1P10 →	+0.097	+4.247	<.001	.007	3	2
HNSC	TEKT4P3 →	+0.568	+5.182	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,033 associations by consensus.

Exploration

NKRF survival (RNA) · tumor vs normal (RNA) · all NKRF data types