NKPD1

Across TCGA cell cohorts, NKPD1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NKPD1-associated genes across cancer lineages are MAGEB4, C8A, and ABCG4. Each is linked with NKPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKPD1-to-partner and partner-to-NKPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by NKPD1-low versus NKPD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKPD1→partner) and Y-score (partner→NKPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.011	+3.415	<.001	.001	3	1
LARGE_INTESTINE	C8A →	+0.018	+2.777	<.001	.004	3	1
LARGE_INTESTINE	ABCG4 →	+0.270	+3.674	<.001	.001	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.192	+3.459	<.001	.005	3	1
LARGE_INTESTINE	FAM136A →	+0.573	+3.067	.001	.009	3	1
BLOOD_Lymphoma	BANF2 →	+0.057	+4.058	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

MAGEB4 by NKPD1 expression — LARGE_INTESTINE

Explore this box plot interactively →