Across TCGA patient cohorts, NKIRAS1 mutation is significantly associated with the RNA expression of many other genes, with 322 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKIRAS1-associated genes across cancer lineages are RPL34P3, SNORD31B, and MIR493. Each is linked with NKIRAS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKIRAS1-to-partner and partner-to-NKIRAS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKIRAS1→partner) and Y-score (partner→NKIRAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPL34P3 →	+0.280	+5.505	<.001	.004	3	2
UCEC	SNORD31B →	+0.430	+3.845	<.001	.001	3	2
UCEC	MIR493 →	+0.238	+4.276	<.001	.005	3	2
UCEC	RNA5SP213 →	+0.593	+3.386	<.001	.004	3	2
UCEC	SRGAP3-AS3 →	+0.308	+2.337	.001	.005	3	2
UCEC	GXYLT1P1 →	+0.062	+4.010	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 322 associations by consensus.

Exploration

NKIRAS1 survival (RNA) · tumor vs normal (RNA) · all NKIRAS1 data types