NKD2

Across TCGA patient cohorts, NKD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,182 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NKD2-associated proteins across cancer lineages are VCL_S290, MFAP2, and MMP2. Each is linked with NKD2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NKD2-to-partner and partner-to-NKD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKD2 versus VCL_S290 in PDAC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKD2→partner) and Y-score (partner→NKD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	VCL_S290 →	+0.956	+0.712	.001	.006	3	7
BRCA	MFAP2 →	+0.763	+1.035	<.001	<.001	3	6
OV	MMP2 →	+0.840	+1.599	<.001	<.001	3	6
PDAC	OMD →	+1.384	+1.037	<.001	<.001	3	6
OV	P3H3 →	+0.655	+1.304	<.001	<.001	3	6
BRCA	PALM →	+0.703	+1.366	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,182 associations by consensus.

NKD2 vs VCL_S290 — PDAC

Explore this scatter interactively →