Across TCGA patient cohorts, NKAPL mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAPL-associated genes across cancer lineages are FASN, Raptor, and HSP70. Each is linked with NKAPL in more than 2 cancer types. Because this analysis shows association rather than direction, both NKAPL-to-partner and partner-to-NKAPL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAPL→partner) and Y-score (partner→NKAPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FASN →	+0.404	+2.230	.006	.006	3	3
LUSC	Raptor →	+0.314	+2.816	.008	.036	3	2
UCEC	HSP70 →	-0.265	-1.492	.039	.027	3	2
UCEC	Ku80 →	+0.152	+1.083	.044	.041	3	2
UCEC	MEK1 →	+0.378	+2.058	.001	<.001	3	2
UCEC	Mre11 →	-0.064	-1.847	.018	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

NKAPL survival (RNA) · tumor vs normal (RNA) · all NKAPL data types