NKAPD1

Across TCGA patient cohorts, NKAPD1 mutation is significantly associated with the RNA expression of many other genes, with 3,925 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAPD1-associated genes across cancer lineages are MIR188, RN7SKP151, and RNA5SP411. Each is linked with NKAPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAPD1-to-partner and partner-to-NKAPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR188 grouped by NKAPD1-low versus NKAPD1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAPD1→partner) and Y-score (partner→NKAPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR188 →	+0.363	+5.837	<.001	.001	3	2
CESC	RN7SKP151 →	+0.334	+4.760	<.001	.003	3	2
UCEC	RNA5SP411 →	+0.969	+1.953	<.001	<.001	3	2
UCEC	RNA5SP412 →	+0.587	+2.159	<.001	<.001	3	2
BRCA	RNA5SP147 →	+0.462	+6.324	<.001	.001	3	2
BLCA	RN7SL543P →	+0.215	+3.926	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,925 associations by consensus.

MIR188 by NKAPD1 expression — CESC

Explore this box plot interactively →