NKAPD1

Across TCGA cell cohorts, NKAPD1 mutation is significantly associated with the RNA expression of many other genes, with 507 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NKAPD1-associated genes across cancer lineages are GGA1, DEPDC5, and DNAL4. Each is linked with NKAPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAPD1-to-partner and partner-to-NKAPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGA1 grouped by NKAPD1-low versus NKAPD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAPD1→partner) and Y-score (partner→NKAPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GGA1 →	+0.792	+3.502	<.001	.001	3	1
LARGE_INTESTINE	DEPDC5 →	+0.552	+3.502	.004	.001	3	1
LARGE_INTESTINE	DNAL4 →	+0.530	+3.321	.004	.003	3	1
LARGE_INTESTINE	RPL3 →	+0.520	+3.502	.002	.001	3	1
LARGE_INTESTINE	TNRC6B →	+0.874	+3.386	<.001	.001	3	1
LARGE_INTESTINE	SGSM3 →	+0.773	+3.137	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 507 associations by consensus.

GGA1 by NKAPD1 expression — LARGE_INTESTINE

Explore this box plot interactively →