NKAIN4

Across TCGA cell cohorts, NKAIN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,576 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NKAIN4-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with NKAIN4 in more than 8 cancer types. Because this analysis shows association rather than direction, both NKAIN4-to-partner and partner-to-NKAIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by NKAIN4-low versus NKAIN4-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN4→partner) and Y-score (partner→NKAIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of syncytium formation by plasma membrane fusion →	+0.048	+0.577	<.001	.003	3	9
LUNG_NSCLC_LUAD	Negative regulation of myoblast fusion →	+0.047	+0.577	<.001	.003	3	7
LUNG_NSCLC_LUAD	Regulation of syncytium formation by plasma membrane fusion →	+0.039	+0.587	.002	.003	3	7
STOMACH	Heparan sulfate proteoglycan catabolic process →	+0.107	+0.887	<.001	.006	3	6
KIDNEY	Cellular response to nutrient levels →	+0.047	+1.581	<.001	.005	3	6
SOFT_TISSUE	Regulation of mRNA processing →	+0.082	+2.297	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,576 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by NKAIN4 expression — LUNG_NSCLC_LUAD

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