NKAIN4

Across TCGA cell cohorts, NKAIN4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NKAIN4-associated genes across cancer lineages are OTOP3, OR5M11, and NEXMIF. Each is linked with NKAIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN4-to-partner and partner-to-NKAIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OTOP3 grouped by NKAIN4-low versus NKAIN4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN4→partner) and Y-score (partner→NKAIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OTOP3 →	+0.019	+3.930	<.001	.003	3	1
SKIN	OR5M11 →	+0.057	+4.437	<.001	.004	3	1
SKIN	NEXMIF →	+0.120	+4.510	<.001	.001	3	1
CNS	KIR2DL3 →	+0.021	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OTOP3 by NKAIN4 expression — SKIN

Explore this box plot interactively →