NKAIN3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NKAIN3 mutation is significantly associated with the RNA expression of many other genes, with 1,800 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAIN3-associated genes across cancer lineages are SLC25A4, GUF1, and ATP5MC3. Each is linked with NKAIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN3-to-partner and partner-to-NKAIN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN3→partner) and Y-score (partner→NKAIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSLC25A4 →+0.453+1.789.004.00732
UCECGUF1 →+0.557+2.457<.001.00132
UCECATP5MC3 →+0.425+2.375.007<.00132
UCECSYNJ1 →+0.320+2.354.009<.00132
SKCMH2AZ1 →+0.848+2.604<.001.00632
UCECRFC1 →+0.602+3.939<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,800 associations by consensus.

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