Across TCGA patient cohorts, NKAIN3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAIN3-associated genes across cancer lineages are Caspase-7-cleavedD198, SCD, and EGFR_pY1068. Each is linked with NKAIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN3-to-partner and partner-to-NKAIN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN3→partner) and Y-score (partner→NKAIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.875	+3.604	<.001	.001	3	2
SKCM	SCD →	+0.162	+3.000	.033	.035	3	1
UCEC	EGFR_pY1068 →	-0.232	-1.874	.021	.049	3	1
UCEC	eIF4G →	+0.296	+1.906	.017	.016	3	1
UCEC	Rad50 →	-0.236	-3.308	.015	.009	3	1
UCEC	Shc_pY317 →	-0.154	-1.906	.011	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

NKAIN3 survival (RNA) · tumor vs normal (RNA) · all NKAIN3 data types