Across TCGA patient cohorts, NKAIN2 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAIN2-associated genes across cancer lineages are eEF2, Paxillin, and FoxM1. Each is linked with NKAIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN2-to-partner and partner-to-NKAIN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN2→partner) and Y-score (partner→NKAIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.374	+2.321	.037	.035	3	2
SKCM	Paxillin →	+0.388	+2.700	.034	.006	3	1
UCEC	FoxM1 →	+0.258	+3.459	.047	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.123	-2.312	.049	.034	3	1
UCEC	GAPDH →	+0.580	+2.321	.031	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.232	-2.308	.006	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

NKAIN2 survival (RNA) · tumor vs normal (RNA) · all NKAIN2 data types