NIT1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NIT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,802 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NIT1-associated proteins across cancer lineages are BROX, RPRD2_T732, and PRCC. Each is linked with NIT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NIT1-to-partner and partner-to-NIT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIT1 versus BROX in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NIT1→partner) and Y-score (partner→NIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCBROX →+0.399+0.408<.001<.00137
LSCCRPRD2_T732 →+0.656+0.472<.001.00136
LUADPRCC →+0.363+0.441<.001<.00136
CCRCCRPRD2_S928 →+0.456+0.362<.001<.00135
LUADSNX27 →+0.197+0.397<.001<.00135
LSCCADAR →+0.291+0.436<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,802 associations by consensus.

NIT1 vs BROX — LSCC

Per-sample scatter of NIT1 vs BROX in LSCC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration