NIPSNAP3A

Across TCGA cell cohorts, NIPSNAP3A protein abundance is significantly associated with the go_rna of many other GO terms, with 3,264 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NIPSNAP3A-associated GO terms across cancer lineages are Regulation of endosome organization, Regulation of lysosome size, and Regulation of pH. Each is linked with NIPSNAP3A in more than 5 cancer types. Because this analysis shows association rather than direction, both NIPSNAP3A-to-partner and partner-to-NIPSNAP3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endosome organization grouped by NIPSNAP3A-low versus NIPSNAP3A-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPSNAP3A→partner) and Y-score (partner→NIPSNAP3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of endosome organization →	+0.164	+0.693	.001	.001	3	6
LARGE_INTESTINE	Regulation of lysosome size →	+0.072	+0.568	.003	.009	3	5
SKIN	Regulation of pH →	+0.075	+0.847	<.001	<.001	3	5
LUNG_NSCLC_LUSC	Proteinogenic amino acid biosynthetic process →	-0.128	-0.975	.001	.002	3	5
BREAST	Regulation of D-glucose import across plasma membrane →	+0.078	+0.793	.001	.001	3	5
BREAST	mRNA transport →	-0.075	-0.703	.002	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,264 associations by consensus.

Regulation of endosome organization by NIPSNAP3A expression — BLOOD_Lymphoma

Explore this box plot interactively →