NIPSNAP2

Across TCGA pan-cancer cohorts, NIPSNAP2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NIPSNAP2 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NIPSNAP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NIPSNAP2 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, UCEC, and CCRCC are the cancer types where NIPSNAP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.911	.012	72	view →
UCEC	OS	Tertile	All	0.873	1.000	.034	20	view →
CCRCC	OS	Median	All	0.822	0.972	.016	13	view →
PDAC	OS	Median	All	0.560	0.411	.048	2	view →
HNSC	DFS	Median	III,IV	1.000	0.939	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NIPSNAP2–COAD (DFS)

Open the COAD breakdown →