NIPSNAP2

Across TCGA cell cohorts, NIPSNAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,951 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NIPSNAP2-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, L-serine biosynthetic process, and Meiotic mismatch repair. Each is linked with NIPSNAP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both NIPSNAP2-to-partner and partner-to-NIPSNAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by NIPSNAP2-low versus NIPSNAP2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPSNAP2→partner) and Y-score (partner→NIPSNAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of isotype switching to IgG isotypes →	+0.137	+0.653	<.001	<.001	3	13
PANCREAS	L-serine biosynthetic process →	+0.207	+0.863	<.001	<.001	3	13
OVARY	Meiotic mismatch repair →	+0.112	+0.796	<.001	<.001	3	11
SOFT_TISSUE	Regulation of telomeric D-loop disassembly →	+0.086	+0.839	.003	<.001	3	11
BONE	Intraciliary anterograde transport →	+0.096	+1.052	.004	.004	2	10
OESOPHAGUS	Transport along microtubule →	+0.044	+0.898	.005	.006	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,951 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by NIPSNAP2 expression — OVARY

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