Across TCGA patient cohorts, NIPSNAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NIPSNAP1-associated genes across cancer lineages are THOC5, ACO2, and KCNJ8. Each is linked with NIPSNAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NIPSNAP1-to-partner and partner-to-NIPSNAP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPSNAP1→partner) and Y-score (partner→NIPSNAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	THOC5 →	+0.588	+0.456	<.001	<.001	3	5
GBM	ACO2 →	+0.487	+0.346	<.001	<.001	3	5
CCRCC	KCNJ8 →	-0.803	-0.277	<.001	.008	3	5
GBM	NGEF →	+1.131	+0.256	.001	<.001	3	5
OV	ARHGEF6 →	-0.887	-0.458	<.001	.001	3	5
GBM	CYP1B1 →	-1.182	-0.267	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,641 associations by consensus.

Exploration

NIPSNAP1 survival (RNA) · tumor vs normal (RNA) · all NIPSNAP1 data types