NIPAL4

Across TCGA cell cohorts, NIPAL4 mutation is significantly associated with the drug of many other genes, with 47 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NIPAL4-associated genes across cancer lineages are Mirin, 150412, and GW-2580. Each is linked with NIPAL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIPAL4-to-partner and partner-to-NIPAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mirin grouped by NIPAL4-low versus NIPAL4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPAL4→partner) and Y-score (partner→NIPAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mirin →	+0.414	+2.868	.020	.022	3	1
LARGE_INTESTINE	150412 →	+0.426	+3.000	.006	.017	2	2
LARGE_INTESTINE	GW-2580 →	+0.383	+2.786	.002	.037	3	1
LARGE_INTESTINE	BX-912 →	+0.685	+2.652	.018	.045	3	1
LARGE_INTESTINE	Quizartinib →	+0.467	+2.652	.003	.045	3	1
LARGE_INTESTINE	Selisistat →	+0.270	+2.652	.006	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Mirin by NIPAL4 expression — LARGE_INTESTINE

Explore this box plot interactively →