NIPAL3

Across TCGA patient cohorts, NIPAL3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,991 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NIPAL3-associated genes across cancer lineages are PLPP2, RAB11FIP4, and TMEM129. Each is linked with NIPAL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NIPAL3-to-partner and partner-to-NIPAL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIPAL3 versus PLPP2 in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPAL3→partner) and Y-score (partner→NIPAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLPP2 →	+0.936	+0.710	.005	<.001	3	4
GBM	RAB11FIP4 →	+0.794	+0.395	.001	.006	3	3
BRCA	TMEM129 →	+0.505	+0.430	.005	.006	3	3
HNSC	MFSD6 →	+0.900	+0.414	.002	.002	3	3
HNSC	TMC4 →	+1.177	+0.393	<.001	.003	3	3
PDAC	ENOX1-AS1 →	-0.558	-0.376	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,991 associations by consensus.

NIPAL3 vs PLPP2 — GBM

Explore this scatter interactively →