NIPAL1

Across TCGA patient cohorts, NIPAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 362 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NIPAL1-associated genes across cancer lineages are RASL10A, PDGFB, and SPRTN. Each is linked with NIPAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIPAL1-to-partner and partner-to-NIPAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIPAL1 versus RASL10A in HNSC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPAL1→partner) and Y-score (partner→NIPAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RASL10A →	-0.921	-1.046	.004	.001	3	1
HNSC	PDGFB →	-1.055	-1.038	.001	.001	3	1
HNSC	SPRTN →	-0.390	-0.735	.003	.007	3	1
HNSC	WDR59 →	-0.586	-0.938	.001	.002	3	1
HNSC	SYDE1 →	-0.731	-1.115	.005	.005	3	1
HNSC	RASIP1 →	-1.386	-1.041	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 362 associations by consensus.

NIPAL1 vs RASL10A — HNSC

Explore this scatter interactively →