NIPA2P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NIPA2P2 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated NIPA2P2 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher NIPA2P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NIPA2P2 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

PAAD, KIRC, and PCPG are the cancer types where NIPA2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADDFSTertileAll0.2310.480.01263view →
KIRCDFSTertileIV0.1270.619.00836view →
PCPGOSTertileAll0.0780.955<.00136view →
UCECDFSTertileAll0.7480.902.00236view →
OVDFSTertileIII,IV0.2850.140.02236view →
SARCDFSTertileAll0.1350.617<.00130view →
READOSTertileIII,IV0.3280.751.00327view →
UCSOSTertileAll0.1850.686.03418view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

NIPA2P2–PAAD (DFS)

Kaplan–Meier survival curve for NIPA2P2 RNA-high vs -low samples in PAAD.

Open the PAAD breakdown →

Exploration