Across TCGA pan-cancer cohorts, NIPA2P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of NIPA2P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NIPA2P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NIPA2P1 is over-expressed in tumor.

KIRC, KIRP, and THCA are the cancer types where NIPA2P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NIPA2P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.612	<.001	11	view →
KIRP	Male	II,III,IV	+0.052	.024	3	view →
THCA	Female	All	+0.049	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: NIPA2P1 RNA expression & survival · all NIPA2P1 data types