NIPA2

Across TCGA cell cohorts, NIPA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,471 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NIPA2-associated GO terms across cancer lineages are Regulation of translation at postsynapse, modulating synaptic transmission, Regulation of translation at postsynapse, and Microtubule nucleation. Each is linked with NIPA2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NIPA2-to-partner and partner-to-NIPA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation at postsynapse, modulating synaptic transmission grouped by NIPA2-low versus NIPA2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPA2→partner) and Y-score (partner→NIPA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of translation at postsynapse, modulating synaptic transmission →	+0.139	+1.020	<.001	.001	3	14
OESOPHAGUS	Regulation of translation at postsynapse →	+0.174	+1.116	<.001	<.001	3	14
BONE	Microtubule nucleation →	+0.080	+0.553	.005	.001	3	12
BLOOD_Leukemia	Negative regulation of cell cycle process →	+0.061	+0.700	<.001	<.001	3	11
BLOOD_Myeloma	Double-strand break repair via nonhomologous end joining →	+0.050	+0.991	.004	.004	2	12
BLOOD_Leukemia	Negative regulation of cell cycle phase transition →	+0.063	+0.681	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,471 associations by consensus.

Regulation of translation at postsynapse, modulating synaptic transmission by NIPA2 expression — OESOPHAGUS

Explore this box plot interactively →