NIP7

Across TCGA patient cohorts, NIP7 protein abundance is significantly associated with the RNA expression of many other genes, with 19,457 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NIP7-associated genes across cancer lineages are CDCA3, KIF20A, and NCAPH. Each is linked with NIP7 in more than 8 cancer types. Because this analysis shows association rather than direction, both NIP7-to-partner and partner-to-NIP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIP7 versus CDCA3 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIP7→partner) and Y-score (partner→NIP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDCA3 →	+0.870	+0.395	<.001	<.001	3	9
UCEC	KIF20A →	+0.911	+0.266	<.001	<.001	3	9
GBM	NCAPH →	+0.734	+0.198	<.001	.002	3	9
UCEC	TROAP →	+0.914	+0.303	<.001	<.001	3	9
BRCA	KIF23 →	+0.891	+0.570	<.001	<.001	3	9
LUAD	CDCA5 →	+1.165	+0.512	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,457 associations by consensus.

NIP7 vs CDCA3 — BRCA

Explore this scatter interactively →