NIP7

Across TCGA cell cohorts, NIP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,159 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NIP7-associated GO terms across cancer lineages are RNA 5'-end processing, Maturation of SSU-rRNA, and 'de novo' UMP biosynthetic process. Each is linked with NIP7 in more than 17 cancer types. Because this analysis shows association rather than direction, both NIP7-to-partner and partner-to-NIP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 5'-end processing grouped by NIP7-low versus NIP7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIP7→partner) and Y-score (partner→NIP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA 5'-end processing →	+0.113	+0.934	<.001	<.001	3	18
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.130	+0.915	<.001	<.001	3	18
OESOPHAGUS	'de novo' UMP biosynthetic process →	+0.163	+1.267	.008	.001	3	17
SKIN	Termination of RNA polymerase I transcription →	+0.127	+0.660	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	RNA modification →	+0.043	+0.565	<.001	<.001	3	16
OESOPHAGUS	Positive regulation of rRNA processing →	+0.142	+1.380	.005	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

RNA 5'-end processing by NIP7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →