NINJ2

Across TCGA patient cohorts, NINJ2 mutation is significantly associated with the RNA expression of many other genes, with 415 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NINJ2-associated genes across cancer lineages are RN7SL542P, ILF2P2, and ATF4P2. Each is linked with NINJ2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NINJ2-to-partner and partner-to-NINJ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL542P grouped by NINJ2-low versus NINJ2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NINJ2→partner) and Y-score (partner→NINJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL542P →	+0.134	+4.822	<.001	.006	3	3
HNSC	ILF2P2 →	+0.049	+4.346	.003	.007	3	2
UCEC	ATF4P2 →	+0.030	+2.599	<.001	.009	3	2
BRCA	RN7SKP157 →	+0.138	+8.055	<.001	.007	3	2
CESC	SNX2P2 →	+0.087	+5.252	<.001	.002	3	2
CESC	PABPC1P13 →	+0.017	+5.252	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 415 associations by consensus.

RN7SL542P by NINJ2 expression — HNSC

Explore this box plot interactively →